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GW 542573X
CAS No. 660846-41-3
GW 542573X( —— )
Catalog No. M33861 CAS No. 660846-41-3
GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 82 | Get Quote |
|
| 5MG | 122 | Get Quote |
|
| 10MG | 211 | Get Quote |
|
| 25MG | 426 | Get Quote |
|
| 50MG | 710 | Get Quote |
|
| 100MG | 945 | Get Quote |
|
| 500MG | 1881 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGW 542573X
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NoteResearch use only, not for human use.
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Brief DescriptionGW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.
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DescriptionGW542573X is a potent and selective Ca2+-activated K+ 2 (SK2) channels activator. GW542573X induces the Ca2+-response curve of hSK1 that left-shifted from an EC50 (Ca2+) value of 410 nM to 240 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorPotassium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number660846-41-3
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Formula Weight364.44
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Molecular FormulaC19H28N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (342.99 mM; Ultrasonic )
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SMILESN(C(OCC1CCN(C(OC(C)(C)C)=O)CC1)=O)C2=C(OC)C=CC=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hougaard C, et, al. Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment. Mol Pharmacol. 2009 Sep;76(3):569-78.?
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